The study, by Dr. Adam Gustafson of Boston University Medical Center in Boston, and colleagues was titled, "Airway PI3K Pathway Activation Is an Early and Reversible Event in Lung Cancer Development." ...

A groundbreaking study led by USC Assistant Professor of Computer Science Ruishan Liu has uncovered how specific genetic ...

Murine Kras-driven lung cancer models have confirmed the key requirements for RAF, PI3K and RAL-GEF in vivo. Co-opted pathways required by oncogenic KRAS in order to sustain lung tumorigenesis ...

Together, these studies uncover novel compensatory pathways ... displace PI3K from active KRAS. In addition, active KRAS may engage non-RAF effectors in specific subpopulations of cancer cells ...

Low-dose aspirin significantly reduced risk for colorectal cancer recurrence among patients with mutations in the PI3K ...

Aspirin reduced colorectal cancer recurrence risk by 50% in patients with PIK3CA mutations over three years. Mutations in the PI3K pathway predict aspirin response, broadening its use to more patients ...

Dr. Suneel Kamath discusses the ALASCCA study in colorectal cancer and highlighted the importance of next-generation sequencing and testing.

HOUSTON -- Two-thirds of patients with PI3K ... effect in cancer cells. The currently available devices have approved indications in glioblastoma, mesothelioma, and non-small cell lung cancer.

Murine Kras-driven lung cancer models have confirmed the key requirements for RAF, PI3K and RAL-GEF in vivo. Co-opted pathways required by oncogenic KRAS in order to sustain lung tumorigenesis ...