Darovasertib, a protein kinase inhibitor C (PKC) being evaluated in neoadjuvant uveal melanoma (UM), has achieved a tumour ...
(I, J) WB and qRT-PCR confirmed that selective protein kinase C inhibitor GO 6983 (10 μM) could inhibit the activation of ERK1/2 and the expression of HBEGF, AREG, and EREG in endothelial cells ...
Preclinical studies and early clinical trials have shown that the anticancer agent tamoxifen, a relatively selective PKC inhibitor that can cross the blood–brain barrier, exerts an antimanic ...