Recently, scientists have been able to explore gene circuitry in individual cells using methods that suppress particular ...

Both studies were enabled by "Worm Perturb-Seq" (WPS), a novel high-throughput method used to deplete the expression of around 900 metabolic genes individually in C. elegans. WPS uses RNA ...

We played a foundational role in developing the Perturb-seq approach for single-cell CRISPR screening and continue to develop new approaches to enable functional genomics experiments beyond ...

Both studies were enabled by “Worm Perturb-Seq” (WPS), a novel high-throughput method used to deplete the expression of around 900 metabolic genes individually in C. elegans. WPS uses RNA ...

ChiP-seq, Perturb-seq and spatial transcriptomic experiments with genetic association studies (GWAS, WES) to enhance our understanding of the functional architecture of all heritable complex diseases, ...

Broad Clinical Labs will use this leading workflow alongside state-of-the-art techniques like Perturb-seq, CRISPR screens and other cutting-edge applications. Together, these capabilities will ...

"The capabilities we're building, like combining Perturb-seq with Illumina Single Cell 3' RNA Prep, will support rapid and consistent data generation like we've demonstrated in the whole genome space, ...

"The capabilities we're building, like combining Perturb-seq with Illumina Single Cell 3' RNA Prep, will support rapid and consistent data generation like we've demonstrated in the whole genome ...