Researchers found a protein that's essential for an enterovirus to enter human cells. Although not the infamous example—that ...

Learn about our Editorial Policies. When I expressed the different protein constructs in neuron cells in culture, I demonstrated that these C-terminal tails determined the localization of the ...

Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane-bound hCoV-229E spike protein bound to its host receptor, human ...

Synaptic plasticity is the basis of information storage in the brain. Two of the most studied forms of plasticity, long-term potentiation (LTP) and long-term depression (LTD), involve both ...

Signaling by type I cytokines involves the formation of receptor homodimers ... receptor γ chain (γ c). Binding and crosslinking experiments demonstrate that this protein is the receptor ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...