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Several RNA binding domains are frequently part of the same protein, but the DND1 domain arrangement is only found in two other proteins. RNA immunoprecipitation experiments showed an essential ...
The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology. As critical regulators of gene expression ...
Extending this discovery recently in Cell, Flynn and colleagues showed that glycoRNAs form highly organized clusters with RNA-binding proteins on the cell surface. These clusters appear to ...
Mutations in or mislocalization of RNA-binding proteins, such as TDP-43 and FUS, are linked to protein aggregation in frontotemporal dementia and amyotrophic lateral sclerosis. Now, researchers led by ...
Yes, say scientists led by Joseph Mazzulli at Northwestern University in Chicago. In the May 17 Neuron, they described how two RNA-binding proteins—one called non-POU domain-containing octamer-binding ...
The interaction between circular RNA (circRNA) and RNA-binding protein (RBP). Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that ...
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How RNA-Binding Proteins and Circular RNAs Shape Tumor BiologyThe interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology. As critical regulators of gene expression ...
Through sequencing analysis, investigators showed that methylation strongly influences the binding of TDP-43 to its RNA targets. They also observed highly abundant RNA methylation in the end-stage ...
Led by Ryan Flynn, MD, PhD, assistant professor of stem cell and regenerative biology at Harvard Medical School (HMS), the study identified one RNA-binding protein on the cell surface, NPM1 ...
Extending this discovery recently in Cell, Flynn and colleagues showed that glycoRNAs form highly organized clusters with RNA-binding proteins on the cell surface. These clusters appear to ...
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