The molecular structure of the Nipah virus (NiV) polymerase complex has been resolved by a team of researchers from Guangzhou ...

A team in China led by Zihe Rao at Tsinghua University report the cryo-electron microscopy (cryo-EM) structure of the RNA-dependent RNA polymerase (RdRp), which is a key part of the virus’s ...

which resides in the RNA exit tunnel. Competition between the archaeal homologs of DSIF and TFIIE for binding the polymerase has been described 43. Finally, the Pol II–DSIF EC structure also ...

Ribonucleic Acid (RNA) polymerase is an intermediary enzyme responsible for processing gene sequences into RNA-based genetic material that can be utilized in protein synthesis. In this article, we ...

Because the sequence, structure, and function of multi-subunit RNA polymerase are universally conserved in all organisms -- from bacteria to humans -- understanding the mechanisms of bacterial ...

An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. This image was created by reconstructing X-ray diffraction crystallography ...

The axis of the hybrid is nearly perpendicular to the entering DNA, as in the yeast RNA polymerase II elongation complex 17. The structure contains partly accessible channels, which presumably ...

For the first time, researchers have visualized the three-dimensional structure of the Nipah virus's RNA polymerase—the enzyme responsible for copying the virus's genetic material—at molecular ...

the corresponding discovery for RNA’s structure was published in 1956. The polymerase discoveries followed suit. DNA polymerase was isolated in 1956; RNA polymerase, in 1959. are designed to ...

The current polymerase thought to be used for the ... This suggests the two RdRp enzymes may keep working in the dimer structure, continuing RNA-dependent processes — although the researchers ...

This enables the RNA polymerase (RNAP ... and due to their simple genetic structure, they provided the team with an ideal ...

An RNA's structure determines how the molecule functions ... begin immediately folding as soon as they emerge from the RNA polymerase, the protein complex that synthesizes them.