Merriam Webster amusingly explained RAS Syndrome or Redundant Acronym Syndrome Syndrome, where the last word of an acronym or ...

RTKs can activate Ras, a protein that is tethered to the plasma membrane, by causing it to bind GTP. Once activated, Ras can do a variety of things. In this example, it activates an enzymatic ...

Erasca continues developing novel RAS-pathway cancer drugs, backed by funding through 2027 and promising early results. Find ...

Brain metastasis is emerging as the most serious concern for breast cancer patients. HER2-positive breast cancer is more prone to undergo brain metastasis than other subtypes; notably, there has been ...

Yet, he says, no one had looked at the relationship between these drugs and ACE2. The RAS pathway regulates blood pressure by triggering the release of renin when blood pressure falls. Renin ...

The results demonstrate that compared to avutometinib alone, the FAK inhibitor/avutometinib combination inhibits RAS/MAPK pathway signaling more deeply while also blocking key adaptive resistance ...