Janet Mertz’s work with simian virus 40 DNA during her graduate years was pivotal for developing DNA recombination as we now know it. Berg was awarded one-half of the Nobel Prize in Chemistry in 1980 ...

coli. While Paul Berg received the 1980 Nobel Prize in Chemistry for the first constructed recombinant DNA in vitro, Boyer and Cohen obtained the first patents related to the actual cloning of such ...

Walter Gilbert ’53 at Harvard and Philip A. Sharp at MIT, who each won Nobel Prizes in the 1980s, were leading the charge in recombinant DNA research on the East Coast. As scientists began to ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The Nobel Assembly at the Karolinska ... clarify the events that lead to chromosomal recombination—the reshuffling of genes that occurs during meiosis—and the function of telomeres, the specialized ...

Restriction enzymes are one of the most important tools in the recombinant DNA technology toolbox ... Arber was one of the recipients of the 1978 Nobel Prize in Physiology or Medicine, an award ...

Unlike its DNA repair role in somatic cells, homologous recombination has a distinct role in meiosis in ensuring proper chromosome segregation. In yeast, an early step of the meiotic program is the ...

In the context of the NIH Guidelines for Research Involving Recombinant DNA Molecules, recombinant DNA molecules are defined as either: molecules that are constructed outside living cells by joining ...