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A lower apixaban dose is indicated in patients with an eGFR less than 30 mL/min/1.73 m2, regardless of dialysis status. Impaired kidney function is the principal predictor of hemorrhage in ...
The beneficial effects of apixaban on these primary efficacy and safety outcomes were also consistent in patients with normal or stable poor renal function (<50 mL/min) over time, according to ...
"The present analysis represents the largest experience of anticoagulation therapy in patients with AF and impaired renal function, and the superiority of apixaban relative to warfarin for ...
Back to Healio Renal function status had no effect on the superiority of apixaban in efficacy and safety compared with warfarin in patients with atrial fibrillation, according to data published in ...
“Apixaban appears to be safer across the spectrum of kidney function categories, possibly owing to its predominantly non-renal elimination,” Dr Siontis and his team explained. “The results ...
However, there were no statistically significant differences in any renal outcome with apixaban versus warfarin. Notably, renal function decline is “very common” in this patient group, Yao and ...
Apixaban, an oral, direct factor Xa inhibitor ... of less than 40% in association with the index event, impaired renal function with a calculated creatinine clearance of less than 60 ml per ...
Apixaban oral tablet is available as a brand ... Be sure to avoid doing this when the weather is very hot or very cold. Kidney function. Your doctor may do blood tests to check how well your ...
Other safety outcomes included any bleeding, other adverse events, and liver-function ... of renal impairment, and risk factors for stroke, as well as in other predefined subgroups. Apixaban ...
To explore over- and underdosing, Yao and colleagues followed the labelled recommendations for who should be receiving a reduced dose based on their renal function: creatinine ≥ 1.5 mg/dL for apixaban ...
I take an anticoagulant (5 mg of apixaban daily), so I don’t take ... relievers should at least get yearly checks on their kidney function. Dear Dr. Roach: I’m a 70-year-old woman in fairly ...