Topical retinoids also demonstrate inhibition of various immune factors ... by interacting with nuclear receptors (RARs [retinoic acid receptors] or RXRs [retinoic X receptors]) on cells and ...

A new male contraceptive YCT-529 shows promise with a nonhormonal approach, preventing sperm production without altering ...

OXFORD, England--Orca Pharmaceuticals, a UK based biopharmaceutical company, and AstraZeneca today announced a three year collaboration to develop inhibitors of retinoic acid–related orphan ...

When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment ...

Conversely, when they used specific inhibitors to block the retinoic acid signaling pathway, strobilation was disrupted—even in healthy polyps with an intact microbiome. The researchers also ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...