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The brown adipocyte is a thermogenic cell. Its thermogenic potential is conferred by uncoupling protein-1, which ‘uncouples’ adenosine triphosphate synthesis from energy substrate oxidation.
White adipocytes are mainly located in the abdominal and subcutaneous areas of the body and highly adapted to store excess energy. Conversely, beige and brown adipocytes are highly energy ...
Special fat cells known as brown adipocytes help maintaining body temperature by converting calory-rich nutrients into heat. This protects from gaining excess weight and metabolic disorders.
Higher brown adipose tissue mass is associated with a reduced cardiovascular disease risk in adults and leanness. Beige cells are also thermogenic adipocyte cells that can be induced either ...
including white and 'beige' adipocytes, which share features with brown adipocytes. The origin of beige adipocytes remains unclear. Additionally, the factors maintaining white adipocyte properties ...
Negron et al, Both proliferation and lipogenesis of brown adipocytes contribute to postnatal brown adipose tissue growth in mice, Scientific Reports (2020). DOI: 10.1038/s41598-020-77362-x ...
Conversely, changes in adipocyte function affect systemic metabolism ... with the highest levels in subcutaneous white and brown adipose tissue. 42 FAHFA tissue concentrations are similar to ...
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