H.B. Dear H.B.: The sciatic nerve is the largest nerve in the body ... An imaging study, such as an MRI, is indicated to see what could be causing his symptoms. If his regular doctor is ...

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and did not have any of the muscle atrophy, gait abnormalities, or reduced grip strength that mice in control groups developed. Even mice who underwent heavy sciatic nerve damage benefited from ...

Specifically, transient expression of the pluripotency transcription factor NANOG reprograms the muscle to an embryonic-like state, increases the number of satellite cells and prevents atrophy. In a ...