It has, therefore, been suggested that selective COX-2 inhibitors of the inducible isoform may be free from renal adverse effects. Recent evidence suggests that this may not be so.

The recent withdrawal of rofecoxib (Vioxx) from the market has intensified controversy about the safety of cyclooxygenase (COX)-2 inhibitors. Results from several recently published studies ...

NEW YORK, July 18 (Praxis Press) A new class of nonsteroidal anti-inflammatory drugs selectively inhibits cyclooxygenase (COX)-2 and may produce fewer adverse effects than nonselective inhibitors.

Cyclooxygenase-2 (COX-2) inhibitors have long been employed to modulate inflammatory responses in a range of conditions, from arthritis to malignancies. In recent years, the convergence of ...

In future clinical practice, selective COX-2 inhibitors may serve as a potential therapeutic modality to combat liver fibrosis via ferroptosis inhibition. Source: Xia & He Publishing Inc.

Celecoxib is a selective COX-2 inhibitor used for the management of pain and inflammation associated with various conditions, including osteoarthritis, rheumatoid arthritis, ...

Regarding selective COX-2 inhibitors, none of the studies in the review reported thrombotic cardiovascular events with their use. The COX-2 inhibitor celecoxib showed no increase in bleeding ...

In future clinical practice, selective COX-2 inhibitors may serve as a potential therapeutic modality to combat liver fibrosis via ferroptosis inhibition. Full text https://www.xiahepublishing.com ...

Source Reference: Cahill EP "Adding a COX-2 inhibitor improves efficacy of emergency contraception" Lancet 2023; DOI: 10.1016/S0140-6736(23)01612-4.