Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the pathogenesis and perpetuation of ...

Purpose: The role of sunitinib and sorafenib in the treatment of metastatic renal cell carcinoma (mRCC) is reviewed. Conclusion: The tyrosine kinase inhibitors sorafenib and sunitinib offer ...

"Small-molecule" drugs are up for price caps nine years after hitting the market, versus 13 for large-molecule biologics. This discrepancy could wallop cancer research. It can take drugmakers 15 ...

That prospect is already chilling investment in drug research, particularly in small-molecule drugs. This category of medicines, which are generally chemically synthesized, includes everything ...

Check out Laura’s cover story on small-molecule drugs at cenm.ag/smallmol. Contact Stereo Chemistry: Contact us on social media at @cenmag or email [email protected]. The following is a ...

For small molecule drugs (chemical compounds that are usually pills, e.g. empagliflozin [Jardiance]), prices are negotiated at year 7 and take effect 9 years after FDA approval. For biologics ...

For no clear reason, it draws a distinction between large and small molecule medicines. As part of the IRA’s Medicare price control provisions, price negotiation for small molecule medicines is ...

Earlier this year, they released that data as training fodder in a competition aimed at determining whether any AI models for predicting small molecule interactions with proteins were really ...