Rosuvastatin calcium (Fig. 1) was discovered through the synthesis and screening of a series of pyrimidine-substituted 3,5-dihydroxy-6-heptenoates containing a sulphonyl moiety introduced to lower ...

Rosuvastatin did not reduce the primary outcome ... Statins could also be harmful in these patients because they reduce the synthesis of coenzyme Q10 (a cofactor in the mitochondrial electron ...

rosuvastatin and atorvastatin can be administered at any time of day. Other statins have shorter half-lives and should be administered in the evening, when synthesis of endogenous cholesterol occurs.

Thirty-four participants assigned to rosuvastatin had symptomatic VTE after a median follow-up of 1.9 years, compared with 60 assigned to placebo (HR=0.57; 95% CI, 0.37-0.86).

Treatment with the anticholesterol medicine rosuvastatin calcium did not reduce the risk of fracture among men and women who had elevated levels of an inflammatory biomarker, according to a report.

A head-to-head comparison of two popular lipid-lowering medications suggests that rosuvastatin may be a better option than atorvastatin when it comes to decreasing the risk of all-cause mortality and ...

Increased levels of the inflammatory biomarker high-sensitivity C-reactive protein predict cardiovascular events. Since statins lower levels of high-sensitivity C-reactive protein as well as ...