A meta-analysis showed that the use of oral tranexamic acid along with the standard triple combination cream (TCC) reduces melasma severity and recurrence in patients with melasma, without ...

The author suggests studying other pharmaceutical preparations of Silymarin like gel or paint and other dosing intervals in the treatment of melasma.

Melasma scores improved by 40%, 57% and 63% at days 30, 60 and 90, respectively. Adverse events were reported in six of the 50 subjects. A novel nano-formulated combination cream composed of ...