"Importantly, we found that c-Maf, a transcription factor that has been reported to be involved in Tfh cell differentiation, exerts a critical function specifically in the transition step from pre ...

Kinetic analyses revealed that influenza nucleoprotein (NP)-specific BRMs differentiated early after infection and required T follicular helper (Tfh) cell help. BRM differentiation coincided with ...

the IL-2-non-producing T cells induced genes characteristic of non-Tfh effector cell differentiation. This suggested that IL-2 producers were fated to become Tfh cells, and IL-2 non-producers were ...

"But occasionally, one sees species differences, and Tfh cell differentiation was one of those cases." Finally, the team showed that for activin A to stimulate Tfh maturation it must activate ...

Several prominent cytokines positively or negatively regulate Tfh cell differentiation and development. Sino Biological has developed a comprehensive collection of high-quality cytokines that support ...

What role do the Tfh cells play? The UAB researchers found that the preferential differentiation of lung-BRMs early after infection correlated with differences in the Tfh cell response early in ...

naive T-cell differentiation into type 17 helper T (Th17) cells and type 17 cytotoxic T (Tc17) cells, follicular helper T (Tfh) cells (see the Glossary) and follicular regulatory T (Tfr ...

"But occasionally, one sees species differences, and Tfh cell differentiation was one of those cases." Finally, the team showed that for activin A to stimulate Tfh maturation it must activate ...

The T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells essential for the survival, affinity maturation, and class switch recombination of B cells. They promote effective B-cell ...

What role do the Tfh cells play? The UAB researchers found that the preferential differentiation of lung-BRMs early after infection correlated with differences in the Tfh cell response early in the ...