Only two calcineurin inhibitors exist, cyclosporine and tacrolimus, and the available formulations are once-daily slow-release tacrolimus, twice-daily immediate-release tacrolimus and twice-daily ...

Background: Tacrolimus and cyclosporine, both calcineurin inhibitors, can cause neurological side effects. While mild symptoms such as tremor are well recognised, severe complications including ...

It is developing LP-10, a formulation of tacrolimus that is in Phase IIa clinical ... one of North America’s leading platforms for micro-cap insights. Catering to both Canadian and U.S. markets ...

The use of twice-daily immediate-release tacrolimus in lung transplant recipients is associated with lower rates of chronic lung allograft dysfunction and improved overall survival compared to ...

Aim: Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation. Patients & methods: We performed a ...

Only two calcineurin inhibitors exist, cyclosporine and tacrolimus, and the available formulations are once-daily slow-release tacrolimus, twice-daily immediate-release tacrolimus and twice-daily ...

A recent study found that a 24-week course of oral tacrolimus (along with tapering doses of prednisone) might be an effective alternative to ciclosporin in Chinese adults with steroid-dependent ...