well-controlled clinical studies have established the efficacy and safety of initial adjuvant therapy with letrozole or anastrozole versus the previous standard of 5 years of adjuvant tamoxifen ...

at 24 months NA N N [15] Letrozole users (n = 65) had higher cognitive test composite score when compared with tamoxifen users (n = 55) NA Y Y [17] No significant effect on cognition with AI ...

Tamoxifen belongs to a group of drugs known as endocrine agents. It acts as an anti-estrogen in breast tissue by blocking the estrogen required by certain breast cancer cells to grow. Tamoxifen is ...