Continually proliferating cells maintain adequate telomeres through the action of the reverse transcriptase telomerase. Telomeres are important to human health because dysregulation of either telomere ...

and telomerase action (Poisson distribution). The results show that the kinetic behavior is between normal diffusion and anomalous diffusion. Following this, the specific parameters (such as ...

Figure 4b demonstrates how telomerase works. Telomerase binds to the G-tail of the telomere through the RNA template, and it then catalyzes the extension of the G-tail. Only one extension cycle is ...

CASE ALLEGATIONS: Geron is a commercial-stage biopharmaceutical company that focuses on the development of therapeutic products for oncology. According to the complaint, Geron's primary product is a ...

Geron’s primary product is a telomerase inhibitor ... What Now: You may be eligible to participate in the class action against Geron Corporation. Shareholders who want to serve as lead plaintiff ...

The long-term and durable responses observed in the Phase 3 IMerge study reinforce the practice-changing potential of telomerase inhibition as a clinically meaningful and differentiated option for ...

Studies on the role of telomerase in cancer and aging have made many lists of the most important future research areas in biological sciences. Dr. Tollefsbol's laboratory is also interested in the ...

Cell aging has always been an important topic in biological research, and telomere shortening is one of the key issues in ...