Anyone who has developed an affinity for sewing or embroidery knows exactly how quickly piles upon piles of empty thread ...

To get started, thread your line through the guide closest to the reel, open the bail, and then loop the line around the reel’s spool. Finish it off with a simple knot. It doesn’t have to be anything ...

Some histones function as spools for the thread-like DNA to wrap around. Under the microscope in its extended form, chromatin looks like beads on a string. The beads are called nucleosomes.