In a lab in the heart of Boston, professor Bree Aldridge leads a team of researchers trying to understand a threat that is ...

Advanced multiplexed imaging shows in how the immune response to Mtb when unvaccinated is very inflammatory and results in structures called granulomas, which are dense collections of immune cells ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

Preterm births and low birth weights are more frequent among infants with congenital tuberculosis than among those with ...

Different types of immune cells form, so-called granulomas, in which M. tuberculosis can survive for years (latent infection). They fall into a permanently inactive state with reduced metabolic ...

In our case, it was initially difficult to differentiate TB from other focal lesions because patient did not present any other systemic symptoms except for persistent oral ulcer. Considering his ...

More information: Chanchal Sur Chowdhury et al, Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation, Cell Host & Microbe (2024).