Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few ...

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few ...

For example, advanced prostate cancer (PCa) is often linked to changes in the activity of a tumor suppressor, called phosphatase and tensin homologue deleted on chromosome 10 (PTEN), and a widely ...

As a result, the degenerated cell eventually multiplies and a tumor can grow. In about one out of two tumors, such a mutation ...

Researchers have known for some time that the tumor-suppressor gene p53 plays a vital role in the body's struggle to stave off cancer. Exactly how p53 is activated in reponse to DNA damage ...

More information: Karthikeyan Subburayan et al, Tumor suppressor Par-4 activates autophagy-dependent ferroptosis, Communications Biology (2024). DOI: 10.1038/s42003-024-06430-z Journal information ...

uring the 1990s, several labs in the United States and United Kingdom investigated the von Hippel-Lindau tumor suppressor (pVHL). Many important findings developed, including the belief that HIF ...

The abstract, “mRNA Lipid Nanoparticles for Next-Generation Oral Cancer Tumor Suppressor Therapy” was presented during the “AADOCR Hatton: Post-doctoral” Poster Session that took place on ...

Tumor suppressor protein Par-4 triggers unique cell death pathway in cancerous cells. ScienceDaily . Retrieved May 21, 2025 from www.sciencedaily.com / releases / 2024 / 07 / 240723132040.htm ...