Two populations ... base 1-, 2-, and 3-compartment models are summarized in Table 1. As found in the separate modeling of the intravenous and nasal data, the 2-compartment model with an estimated ...

Recently published study focused on the evaluation of a novel etomidate analogue, methoxyethyl etomidate hydrochloride (ET-26), in healthy volunteers to assess its safety, tolerability, ...

Results: The pharmacokinetics of intravenous fentanyl reflected a 2-compartment model with a clearance of approximately 1.5 L/min. There was moderate (< 50%) between-subject variability (BSV ...