Gram-negative bacteria secrete proteins using a type III secretion system (T3SS), which functions as a needle-like molecular machine. The many proteins involved in T3SS construction are tightly ...

Although recent studies have expanded our knowledge on the structure and function of many type III translocated effectors, the precise mechanisms of type III protein secretion and translocation ...

we found that coordinated expression of the type 3 secretion system and modified target protein substrates produces a nonpathogenic strain that expresses, secretes, and delivers heterologous ...

When bacteria such as Salmonella or Yersinia cause fever, diarrhea or abdominal pain, tiny "injection needles" are at work: their type 3 secretion system, or T3SS for short, shoots bacterial ...