Johnson & Johnson said Tuesday it has agreed to acquire V-Wave Ltd., a privately held company developing treatments for patients with heart failure, for $600 million upfront and potential extra ...

Large jugular V waves (Lancisi's sign ... ring is reasonable to severe primary tricuspid regurgitation when right heart failure symptoms are present (class IIa, level of evidence C).

A widened split S2 heart sound can be caused by severe mitral regurgitation, pulmonic stenosis or a right bundle branch block. Large systolic jugular venous pulsations can be from V waves due to ...