and the four major molecular mechanisms implicated in hyperglycemia-induced vascular damage reflect a single process: overproduction of superoxide by the mitochondrial electron transport chain.

Atherosclerosis (AS) is a chronic inflammatory disease characterized by the buildup of lipids and immune cells in arterial ...

The blood-brain barrier is a network of blood vessels and tissues that acts as a protective shield, preventing harmful substances in the blood from reaching the brain. In Alzheimer’s disease, this ...

Researchers have revealed that vascular dysfunction can contribute to neurodegenerative diseases including Alzheimer's and ...

A new Canadian study has found that chronic kidney disease (CKD) is linked to lower cognitive performance, affecting ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease and amyotrophic lateral sclerosis ...

COVID-19 affects hundreds of millions of people worldwide and is often associated with long-term neurological abnormalities. Common symptoms include the loss of taste and smell, dizziness, "brain fog" ...