Figure 2: A reinforcing feedback loop of immune reprogramming and tumour vascular normalization. The discovery that activated T cells can induce morphological and functional tumour vessel ...

Next, we illustrate some key prototypical underlying mechanisms of vascular normalization, and end by discussing the initial clinical evidence and speculating on the clinical potential of vessel ...

His career has been defined by bold hypotheses and interdisciplinary research—most notably, his groundbreaking theory of vascular normalization, which challenged conventional wisdom and ...

Founded in 2014, Vasomune has focused on vascular normalization strategies, and has progressed the lead candidate AV-001 from bench to bedside. Vascular dysfunction is associated with the ...