Febuxostat is a novel non-purine selective inhibitor of xanthine oxidase for the management of hyperuricemia in patients with gout. The ability of febuxostat to decrease serum uric acid production ...

By effectively blocking the conversion of hypoxanthine and xanthine to uric acid, this antimetabolite markedly reduces serum uric acid levels and thereby diminishes urinary excretion of urates.

the enzyme that catalyzes the oxidation of hypoxanthine to xanthine and xanthine to uric acid, is inhibited by allopurinol, oxipurinol and febuxostat. Allopurinol is a structural analog of ...

Some work by relieving pain and reducing inflammation, while others help lower uric acid and prevent future attacks.

1 Hyperuricemia, elevated serum uric acid levels, can over time result in gout when urate ... serum urate levels in gout patients that are refractory to standard-of-care Xanthine Oxidase Inhibitor ...

Uric acid is naturally present in the body ... which aid the kidneys in flushing urate out of the body Xanthine oxidase ...

Think of the kidneys as a filter—they need plenty of water to flush out uric acid efficiently. But here’s the trick: gulping down a large glass of warm water immediately after waking up starts ...

High uric acid levels can lead to gout and kidney stones, but certain dry fruits can help manage these levels. Including these dry fruits in your diet can be a tasty and effective way to manage ...

Hyperuricemia (HU) is a metabolic disorder characterized by elevated uric acid (UA) levels in the bloodstream, commonly diagnosed when UA levels exceed 420 µmol/L (7 mg/dL) in men and 350 µmol/L (6 mg ...

In a preclinical study, rodents treated with uric acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest that the treatment may work as an add-on therapy to standard ...

1 Hyperuricemia, elevated serum uric acid levels, can over time result in ... in gout patients that are refractory to standard-of-care Xanthine Oxidase Inhibitor (XOI) therapy.

More than half of those patients confirmed exposed to a daily 60 mg dose reached serum uric acid levels below 3mg/dL. Importantly, the study demonstrated an excellent safety profile in this ...