New in vivo detection methods (for example, the current 'green mRNA' approach) will allow us to study localization in living cells, leading finally to the ultimate challenge of trying to ...

View Full Profile. Learn about our Editorial Policies. 3’ UTRs encode information about mRNA localization, translation efficiency, and stability (1). 1 mRNA is packaged with translational machinery ...

In a new study published recently in the journal Cell Reports, Yale researchers reveal that mRNA, or messenger RNA, plays a significant role in cell migration, a duty that also dramatically expands ...

Their results suggest that acetylation of mRNA regulates localization of both stress-sensitive ... of roles for stress granules within the cell have been proposed. While stress granule assembly ...

More information: Yosuke Yoneyama et al, Intercellular mRNA transfer alters the human pluripotent stem cell state, ...

Profiling the expression and subcellular localization of dozens of proteins and mRNA species in approximately one million cells allowed for a nuanced interrogation of variant influences on the DNA ...

One of mRNA’s greatest advantages is the ability to rapidly iterate and optimize sequences, accelerating drug discovery and development. Advances in cell-free gene synthesis and in vitro transcription ...

Although messenger RNA (mRNA) vaccines had been in research and development for many years, the search for a vaccine against SARS-CoV-2 brought them to the forefront. However, alongside the ...

A variety of modifications are typically made to mRNA molecules before they are used further by the cell, usually to generate a protein. Scientists have now learned more about a mysterious RNA ...

implying that m 6 A loss was a characteristic of cells infected with SARS-CoV-2. The nuclear export protein (XPO1) inhibition restored METTL3 localization and SG formation and increased mRNA ...