Like omega-3 fatty acids, C15:0 is considered an essential nutrient that the body cannot produce in sufficient amounts, ...

and that "it is well known that metformin inhibits P13K signalling directly by activating AMPK [AMP-activated protein kinase] ...

K. O'Reilly et al., "mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt," Cancer Res, 66:1500—8, 2006. (Cited in 95 papers) It's known that rapamycin inhibits ...