Although fewer antibody fragments have entered the clinic ... murine) or molecule type (Fab or scFv). Afelimomab, an immunotherapy, is a murine Fab fragment targeting tumor necrosis factor ...

Examples of antibody sequences accepted: variable region sequenced from hybridoma, hits (Fab or scFv) selected from display library based method, sequences from single B cell and/or repertoire ...

In order to demonstrate the functionality of this concept, we have constructed a large human antibody single-chain fragment (scFv) library using these principles. This library has been ...

FMC63, an IgG2a mouse monoclonal antibody, targets CD19. To date, a majority of the reported CART19 trials include the anti-CD19 scFv extracted from FMC63, such as both the FDA-approved CARs ...

Various purified antibody products, including IgGs, Fab, scFv, VHH, bi-specific antibodies, and more, can be delivered in large quantities (i.e., from ug to mg) using the TurboCHO™ High ...