The activated glutamine is coupled to the 5'-OH of the AD02 ribozyme; so, to achieve aminoacylation of tRNA in the second step, the authors had to perform several rounds of thermocycling to allow ...

the initiator methionine tRNA, essential for starting protein synthesis, and a specific glutamine tRNA. This reduction resulted in diminished protein synthesis of key genes in the brain ...

glutamine metabolism, synaptic structure, and memory. LIU and his team shed light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's disease, offering new insights for ...

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...