Importantly, the researchers also noticed unforeseen heterogeneity among the activated cells. They hypothesized that a subset of reactive microglia may be less sensitive to the inflammatory ...

“This work demonstrates for the first time that microglia heterogeneity can be recapitulated in a cell culture dish,” noted Lewcock and Monroe. They were struck by how much human microglial expression ...

Cracking open this heterogeneity is the focus of intense research (see Part 14 of this series). Just like the false dichotomy of M1 versus M2 phenotypes of the past, labeling microglia as “good” or ...

But a lot of us don’t realise that the brain also has an immune system. Microglia, which are the brain’s immune system cells, are involved in everything – from brain development to ...

Known as microglia, these specialised immune cells are our brains’ premier defenders. They protect us from invaders, clear away debris and maintain connections between neurons to ensure the ...

By engineering human immune cells called microglia, the researchers have created living cellular "couriers" capable of responding to brain pathology and releasing therapeutic agents exactly where ...

Microglia, the immune cells of the brain, have long been the underdogs of the glia world, passed over for other, flashier cousins, such as astrocytes. Although microglia are best known for being ...

Researchers coaxed stem cells to grow into microglia, immune cells that roam the brain searching for signs of damage and that monitor and maintain neuronal connections. They then added microglia ...

Microglia are special cells in the human brain. Like a diligent ranger overseeing a forest and dealing with infestations and wildfires, microglia scan the brain environment for germs and initiate ...

But today I’ll confess, I don’t love every cell the same. I have a very favorite kind, the microglia. So it seems like a good time to promote my pet cells. Here, for your thoughtful ...