Mitochondrial stress disrupts insulin production in diabetes, but reversing the damage may restore β-cell function.

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...

List of Confirmed and Putative Signal Transducer and Activator of Transcription (STAT)5-Target Genes in β-cells or Pancreatic Islets (Activated or Repressed Genes) Target genes of prolactin or ...

Researchers at the University of Michigan used mice to show that dysfunctional mitochondria trigger a response that affects ...

Conceptual diagram summarizing the central experiment comparing cell death in amyloid-β treated neuronal cells with and without pancreatic β cell culture supernatant. Pancreas cells may produce ...

The work also suggests strategies to boost B cell responses, target immunosuppressive macrophages and deplete activated ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic cancer cells.

Recently, they have developed a gene switch that can be activated using commercially available nitroglycerine patches. The ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders.

Due to a lack of noticeable symptoms in its early stages and the pancreas’ obscure location behind other organs in the ...