E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

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In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

Stars emerge from vast regions of gas and dust known as molecular clouds. These stellar nurseries, often spanning hundreds of light-years, serve as the birthplace of countless stars, including those ...

Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, ...

The fossilized remains were discovered in the Sterkfontein Caves in South Africa, a site renowned for its wealth of hominid ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

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We also provide several recent examples in which structural and functional analyses were essential for uncovering the molecular ... than the structure of ubiquitin itself in different chain ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...

SACRAMENTO COUNTY, Calif. — CHP is investigating an early-morning crash that closed all northbound lanes of Interstate 5 near Lambert Road in the Walnut Grove area of Sacramento County.