Gout is a disease characterized by recurrent attacks of arthritis, in which uric acid appears in excessive amounts in the ...

Allopurinol is the most commonly prescribed XOI ... XORTX is working to advance products that target aberrant purine metabolism and xanthine oxidase to decrease or inhibit production of uric acid. At ...

Clinical studies have revealed that febuxostat lowers serum uric acid levels more potently than allopurinol while ... associated with purine and pyrimide metabolism. The most frequent adverse ...

Objective: To assess the effect of a combination treatment using anti-hyperuricaemic agents with fenofibrate and/or losartan on uric acid metabolism in hypertriglyceridaemic ... benzbromarone (50 mg ...

Serum fatty acid levels are also altered, leading to changes in fatty acid metabolism, causing mitochondrial dysfunction ... a reduction in the expression of inflammatory molecules when allopurinol or ...

"When the inflammation has settled down, it is important to prevent future attacks. Allopurinol can reduce uric acid levels and therefore the risk of further bouts. There’s also evidence to ...

It is a good idea to leave them unpruned over winter: they provide food and shelter for wildlife and can look attractive even in decay, particularly when sprinkled with frost on cold mornings ...

*Dose registered for erosive esophagitis and gastroesophageal reflux disease. iv.: Intravenous; NA: Nonavailable. Alex Mejia, MD, Department of Pharmacology and Experimental Therapeutics, Division ...