“In a typical resource-limited setting like ours, nobody has an electron microscope,” Aniweh says ... at mapping the molecular architecture of mitochondria, microtubules and single-celled ...

The FDA has extended the review period for the New Drug Application for elamipretide for the treatment of Barth syndrome.

If approved, this would be the first marketing authorization for elamipretide, a first-in-class mitochondria-targeted therapeutic, and the first FDA-approved therapy for Barth syndrome.

Barth syndrome is caused by a mutation in the tafazzin gene, which results in reduced cardiolipin levels, a phospholipid that plays a major role in mitochondrial function. The disease is ...

The US Food and Drug Administration (FDA) has delayed its decision on Stealth BioTherapeutics’ new drug application (NDA) for elamipretide, a treatment for the ultra-rare disease Barth syndrome.

Three months ago, the FDA’s Cardiovascular and Renal Drugs Advisory Committee voted 10-6 in support of elamipretide becoming the first approved treatment for Barth syndrome, an X-linked genetic ...

A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

Most of us remember two things from high school biology: that mitochondria are the powerhouses of cells and that we inherit stable sets of chromosomes from our two parents. Both truisms are only ...

Breaking Taps Wasp inside an Electron Microscope Posted: January 10, 2025 | Last updated: January 10, 2025 Common Hoverfly Parasitoid Wasps! Today we're looking at a wasp I found in my backyard ...