which impairs NK cell degranulation and reduces key cytotoxic markers such as perforin and CD107a in various cancer models, including pancreatic and breast cancers (40–42). Therapeutic strategies that ...

A team of researchers from the Hospital del Mar Research Institute, the Universitat Autònoma de Barcelona and the Pompeu Fabra University has developed a new tool that allows modifying these NK cells ...

A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.

Among other functions, the NK cells (natural killers, a type of lymphocyte forming part of the immune system) have the capacity to detect and eliminate cancer cells. But in some cases they cannot ...

Natural killer cell deficiency should be considered in patients susceptible to herpes virus or papillomavirus with persistently decreased NK cell function.

Gilead Sciences' cell therapy Kite Pharma has bulked up its position in natural killer (NK) cell therapies, pledging up to $2.3 billion for a partnership with Shoreline Bioscience focusing on off ...

Mar. 11, 2025 — Researchers have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences ...

What Is B-Cell Lymphoma? B-cell lymphoma is a cancer that forms in your white blood cells called lymphocytes. These cells are made by your lymphatic system, which plays an important role in immunity.

Certain subsets of immune NK cells were altered in the blood of people with ALS, and could serve as therapeutic targets, a ...