Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

The regulation of the white-cell count is dependent upon many factors controlling production, maturation and release from the bone marrow, distribution in peripheral blood pools and egress to ...

VILNIUS, Lithuania (AP) — Nearly 3 1/2 decades after leaving the Soviet Union, the Baltic countries of Estonia, Latvia and Lithuania this weekend will flip a switch to end electricity-grid ...

RTCB is required for the splicing of both tRNA and XBP1 mRNA, whereas the DDX1 enzymatic activity is specifically required for tRNA splicing in vivo. Snaebjornsson et al. explore a selective ...

Keralite woman's exemplary courage saves husband who fell into deep well According to fire department personnel, Rameshan had pre-existing health issues and was nearly unconscious due to the ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

Hanging drop preparation can be easily employed by flipping a universal 96-well plate. The droplets of the medium generated by the well-plate flip (WPF) method can be easily modified to address ...

The efficacy of CD19-CAR T-cell therapy ... and TFH cells as well as decrease (<90%) of proliferation rate (median B-cell compartment score (IQR): 0 (0–0.5)). This study demonstrates that CD19-CAR ...

Common hematologic abnormalities in patients with SCD include elevated levels of platelets, leukocytes (primarily neutrophils; cell count between 12,000 and 20,000/mm 3), and often reticulocytes.

US tech giant OpenAI on Monday unveiled a ChatGPT tool called "deep research" that can produce detailed reports, as China's DeepSeek chatbot heats up competition in the artificial intelligence field.

The UK government introduced legislation Thursday designed to give law enforcement officials "counter-terror style powers" to break up gangs bringing irregular ...

We study problems that have widespread cybersecurity implications and develop advanced methods and tools to counter large-scale, sophisticated cyber threats. CERT experts are a diverse group of ...