Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the attention of scientists like me. Consider muscle movement. Your body ...

part of the tRNA synthetase enzyme family. The lead candidates are part of the company’s portfolio of proprietary chemical scaffolds, which have shown broad activity against the enzyme class in ...

Support for this hypothesis is found in the observations that high glucose concentrations increase intraislet peroxide levels, that islets contain very low levels of antioxidant enzyme activities ...

Anti-synthetase syndrome is a subtype of idiopathic inflammatory myopathy, and has clinical features including interstitial lung disease, myositis, Raynaud's phenomenon, arthritis, mechanic's hands, ...

Department of Chemistry, Faculty of Natural, Mathematical and Engineering Sciences, King’s College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K. Department of Chemistry, Faculty of ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

Then, protein bands were washed twice in 25 mM AB. Proteolytic digestion was performed by addition of Trypsin (Promega, Madison, WI), 12.5 ng/µl of enzyme in 25 mM AB and incubated at 37 °C overnight.

Although the potential positive aspects of BSH enzymes have been previously discussed (De Smet et al., 1998), other possible negative concerns about them have also been raised, such as disruption of ...

The authors present three transgenic models carrying three representative exon deletions of the dystrophin gene. The findings presented are valuable to the field of muscle diseases, particularly ...

Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States ...