Frontiers23d
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway
Deferoxamine mesylate (HY-B0988, MCE) was dissolved properly, and was given by daily intraperitoneal (i.p) injection at the different doses, including 25 mg/kg/day, 50 mg/kg/day, and 100 mg/kg/day.
Pharmaceutical Technology1mon
Pritelivir mesylate by AiCuris Anti-infective Cures for Simplexvirus (HSV) Infections: Likelihood of Approval
Pritelivir mesylate is under clinical development by AiCuris Anti-infective Cures and currently in Phase III for Simplexvirus (HSV) Infections. According to GlobalData, Phase III drugs for ...
Frontiers2y
SiNPs induce ferroptosis in HUVECs through p38 inhibiting NrF2 pathway
Results and discussion: The results showed that at the tested concentrations, SiNPs could decrease HUVEC viability, but the deferoxamine mesylate (an iron ion chelator) might rescue this reduction of ...