Bacterial small RNA promotes gut colonization by regulating sialic acid metabolism, research reveals
A study published in PNAS reveals how a bacterial pathogen coordinates N-acetylneuraminic acid (Neu5Ac) metabolism at the ...
technologynetworks10d
Novel sRNA Drives Salmonella’s Adaptation in the Host Intestine
A study reveals how Salmonella enterica leverages a small RNA, ManS, to regulate Neu5Ac metabolism and adapt to the host ...
Benitec Biopharma: Early Positive Data, Small Target Market, Little Competition
Benitec has a market cap of $250mn, $67.8mn in cash, and a cash runway of over 10 quarters, but faces risks due to its small ...
eLife3d
TET2-mediated epigenetic modification promotes stress senescence of pancreatic β cells in type 2 diabetes mellitus
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
Le Lézard17d
Clarivate Identifies Eleven Potential Blockbuster and Transformative Drugs in Annual Drugs to Watch Report
Leveraging Alnylam® Pharmaceuticals' ESC-GalNAc conjugate technology, fitusiran could become the first antithrombin-lowering therapy based on a double-stranded RNA molecule ... as respiratory ...
labiotech23d
A surge in deals: GSK bets on ADC, neuro and fibrotic diseases to bolster drug development
Also last month, GSK stretched its position in the RNA space. With several RNA vaccines in development ... This came after its alliance with Touchlight, manufacturer of doggybone DNA – a ...