Elizabeth’s Radiothon Story
Eight-year-old Elizabeth is known as being the life of the party, so it was clear something was off when she was extremely ...
Frontiers5d
Recent advances in understanding the human host immune response in tuberculous meningitis
This influx may lead to further MMP production, particularly from neutrophils, further driving dysfunction ... sn-glycero-3-phosphorylcholine (oxPAPC), a DAMP released by dying cells, and the cyclic ...
Frontiers5d
Complement system part I – molecular mechanisms of activation and regulation
An initial trigger will stimulate the cell to either express a platform protein (properdin for neutrophils or P-selectin for EC and ... actively in the opsonization of pathogens and dying host cells, ...
Nature5d
Granulocyte colony-stimulating factor and neutrophils—forgotten mediators of inflammatory disease
Recent studies have highlighted the functional capacity of neutrophils as powerful mediators of tissue inflammation. Granule-packaged proteases and reactive oxygen intermediates, which are ...
gut.bmj5d
Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment
Neutrophils are major players in innate immune system. Here, we aimed to explore the heterogeneity and pro-tumour mechanisms of neutrophils in PDAC. Design We analysed single-cell transcriptomes of ...