[19] Potentially important platelet mediators include platelet-derived growth factor (PDGF), TGF-beta 1, and epidermal growth ... injury (see section on Extracellular Matrix Degradation, above).

Initiation of Phase 1/2 combination trial with PYX-201, an extracellular ADC targeting Extradomain-B Fibronectin (EDB+FN) and Merck’s KEYTRUDA® ...

Nell-1: Neural epidermal growth factor-like protein ... a protein that regulates fat cell differentiation and metabolism. Extracellular matrix (ECM): A network of proteins and molecules that ...

Epidermal RNA-seq and immunohistochemistry analysis further ... neutrophil chemotaxis, monocyte chemotaxis and extracellular matrix disassembly in PHR subtype. The down-regulated genes involved in ...

1.4 Associated with connective tissue disease, HIV infection, portal hypertension, congenital heart disease, schistosomiasis ALK-1 indicates activin receptor-like kinase 1; BMPR2, bone morphogenetic ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...

Rhobo6, a light microscopy probe, gives scientists an unprecedented look at the extracellular matrix -- the collection of organized molecular structures that fills the spaces between cells in our ...

Cells have surface receptors called integrins that bind to repetitive domains present on the extracellular matrix (ECM) surrounding the cells, allowing them to grow and spread. A new study from the ...

Nearly 40 years ago, researchers identified the epidermal growth factor (EGF) domain as a key component in mussel adhesive proteins. Since then, similar adhesive proteins have been discovered in a ...

Researchers from Tokyo Metropolitan University have developed a way to treat age-related muscular atrophy using regenerative ...