Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

PYX-201, an antibody-drug conjugate (ADC) with a microtubule inhibitor (optimized auristatin) payload that uniquely targets ...

The Role of the Extracellular Matrix (ECM) in Cancer Progression A cancer cell’s ability to dominate its immediate environment, gain increasing access to nutrients, and spread locally relies on key ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Engineered extracellular vesicles play an increasingly important role in the treatment ...

In the article that accompanies this editorial, 16 the authors report clinical outcomes from the Japanese phase III JBCRG-M06/EMERALD trial, which compared first-line eribulin plus dual human ...

Nearly 40 years ago, researchers identified the epidermal growth factor (EGF) domain as a key component in mussel adhesive proteins. Since then, similar adhesive proteins have been discovered in a ...

Keloid scars (KS) and hypertrophic scars (HS) are fibroproliferative wound healing defects characterized by excessive accumulation of extracellular matrix (ECM ... was disrupted proximal to the dermal ...