Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

In these neurotransmitter classes, compounds do not target cell membrane receptor G-protein signal transduction in a manner that provides a single mechanism for improving gastroparesis symptoms. The ...

In these neurotransmitter classes, compounds do not target cell membrane receptor G-protein signal transduction in a manner that provides a single mechanism for improving gastroparesis symptoms. The ...

Bacterial and viral infections activate the signal transduction networks that regulate the innate ... Another focus is to understand the interplay between protein phosphorylation and protein ...

After stirring for 2 h, the resulting solution was centrifuged at 8000 g for 20 minutes at 4 °C to remove the ... Oxidative post-translational modifications of cysteine residues in plant signal ...

Cohen, D.T. Dudley, A.R. Saltiel, "PD098059 is a specific inhibitor of mitogen-activated protein kinase kinase in vitro and ... Saltiel, department of signal transduction, Parke-Davis, Ann Arbor, Mich ...

Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in BMP2 signaling pathways ... If there is one thing that is known about the mechanisms that govern signal transduction, it's that ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

The research has been published in the journal Nature Communications. Adhesion G protein-coupled receptors are a large class of membrane proteins that detect chemical and mechanical stimuli in the ...