For the last 10 years, the only effective treatment for hypophosphatasia (HPP) has been an enzyme replacement therapy that must be delivered by injection three-to-six times each week.

Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.

Genetic medicines could treat certain diseases, however, the current delivery systems available—viral vectors and lipid nanoparticles (LNPs)—pose unique challenges for gene therapy applications. For ...

President Trump signed an executive order on the day of his inauguration that created doubts about the future of a program that helps state Medicaid programs pay for expensive cell and gene therapy.

For recurrent respiratory papillomatosis (RRP), novel gene therapy to jump-start immunity to the human papillomavirus (HPV) ...

Plus, $200,000 for local digital literacy efforts, a $28M renovation to one of UCity Square’s buildings and more money moves.

Innovative synthetic biology techniques are revolutionizing microbiota-based therapies, enhancing microbial functions for ...

The field of cancer research is rapidly evolving, with a growing focus on the intersection of cancer immunology, gene editing, and epigenetics. This ...

Lentiviral self-inactivating vectors are the retroviral vectors with the greatest potential for gene therapy Nondividing cells can be transduced by lentiviral vectors. They possess a low ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

In contrast, online automated counseling presents a viable option for those hesitant to pursue therapy due to stigma or shame ... an autonomous multi-agent framework designed for CBT in single-turn ...

Gene therapy has been available since 2022 for hemophilia B and since 2023 for hemophilia A, yet some major medical institutions have barely treated any patients so far. What’s the holdup?