eLife3d
Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism
The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...
eLife6d
Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources
Southwest United Graduate School, Yunnan Key Laboratory of Cell Metabolism and Diseases, State Key Laboratory of Conservation and Utilization of Bio-resources in Yunnan Center for Life Sciences, ...
ahajournals.org3d
High Glucose Treatment Induces Nuclei Aggregation of Microvascular Endothelial Cells via the foxo1a-klf2a Pathway
Hyperglycemia is a major contributor to endothelial dysfunction and blood vessel damage, leading to severe diabetic microvascular complications. Despite the growing body of research on the underlying ...
Frontiers6d
Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation
The key signaling pathway APP and the top 1 transcription factor PPARG in this subgroup played essential roles in osteoclast proliferation and differentiation. Given the pivotal role of osteoclasts in ...