C&EN23d
Small Molecule Modulators of AMP-Activated Protein Kinase (AMPK) Activity and Their Potential in Cancer Therapy
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...
Nature27d
Solubilization of Mouse Liver Glycogen Synthetase and Phosphorylase during Starvation Glycogenolysis and its Reversal by Cortisol
DURING starvation, glycogenolysis is associated with the release of the enzymes phosphorylase and glycogen synthetase from insoluble granules into the cytoplasm. This event is accompanied by a ...
Nature1mon
Inactivation and Activation of Liver Phosphorylase
THE level of phosphorylase in liver slices represents a balance between inactivation and resynthesis of the active form; epinephrine and glucagon rapidly increase the amount of active ...
C&EN1mon
NesT-NABind: a Nested Transformer for Nucleic Acid-Binding Site Prediction on Protein Surface
School of Information Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Pudong New Area, Shanghai 201210, China Shanghai Institute for Advanced Immunochemical Studies, ...
Frontiers1y
Rapid glycolytic activation accompanying innate immune responses: mechanisms and function
Innate immune responses to pathogens, mediated by activation of pattern recognition receptors and downstream signal transduction cascades, trigger rapid transcriptional and epigenetic changes to ...
Frontiers3y
Hepatopathy Associated With Type 1 Diabetes: Distinguishing Non-alcoholic Fatty Liver Disease From Glycogenic Hepatopathy
The daily necessity to inject exogenous insulin to treat hyperglycemia leads to a relative portal vein insulin deficiency and potentiates hypoglycemia which can induce weight gain, while daily ...